信阳冬凌草甲素和乙素β-环糊精包合物的研究

Study on the Inclusions of Xindonin A-p-cyclodextrin and Xindonin B-β-cyclodextrin

采用沉淀法制备信阳冬凌草甲素和乙素-β-环糊精包合物,通过差示扫描量热法、薄层层析法及比旋光度测定证明了包合物的形成。用连续递变法测定了包合物的组成摩尔比。通过标准曲线测定了包合物的溶解度。

The inclusions compounds of Xindonin A-β-cyclodextrin and Xindonin B-β-cyclodextrin were prepared by the liquid-phase method in aqueous solution. They were confirmed by thin layer chromatography, differential thermal analysis and specific rotation. Changes of ultraviolet spectrum were determined. The composition ratios of inclusion compounds were obtained by the continuous variation method. Solubility of the inclusions were determined.