周围神经或其组织成分移植修复成年哺乳动物视网膜节细胞的损伤

Transplantation of Peripheral Nerves and Their Tissue Constituents to Repair Axotomized Retinal Ganglion Cells in Adult Mammals

本综述重点阐述了移植周围神经或其组织成分雪旺细胞、成纤维细胞和神经营养因子 ,改善成年哺乳动物中枢神经系统抑制神经再生的微环境、增强受损神经元的内在再生潜力 ,以促进节细胞损伤后的存活和轴突再生。

We focus on how peripheral nerves or their tissue constituents including Schwann cells, fibroblasts and neurotrophic factors are used to overcome the unfavorable extrinsic CNS environment and upregulate the intrinsic growth potential of injured neurons for the enhancement of neuronal survival and axonal regeneration of axotomized retinal ganglion cells in adult mammals.