摘要
对中国已发表的１２５个人群Ｒｈ血型系统表型分布频率数据进行了收集和整理。用累积计算法（Ｃｏｕｎｔｉｎｇ ｍｅｔｈｏｄ）重新计算单倍型频率，通过各单倍型的分布差异分析中国不同地区不同民族、人群的遗传差异。分组比较了不同地区汉族和少数民族人群的基因多样度和基因分化度，结果表明南方少数民族和北方少数民族民族亚群体基因多样度有明显差异。用不同方法计算各小组遗传距离并进行聚类分析。最后，计算了除维吾尔族和哈萨克族外的６８个人群间的遗传距离并聚类比较，结果表明Ｒｈ基因单倍型的分布与地理分布基本相符。
In the statistic study of Rh blood group system, whole Chinese data were re-calculated for haplotype frequency and linkage ratio, according to Counting Method. All Chinese majority populations and minority populations were divided into different groups, and variety genetic calculations on their gene diversity and gene differentiation were also calculated. The results shown obvious genetic differences between and among Southern and Northern Chinese populations. UPGMA phylogenetic dendrograms was plotted and the bee demonstrated that the genetic relationship among 68 Chinese populations are well corresponded with their geographical and linguistic distribution.
基金
中国科学院生物科学与生物技术特别支持项目
