摘要
22℃室温中的长爪沙鼠血清T3 和T4 浓度较低 ,肝脏和褐色脂肪组织 (BAT)的T45 脱碘酶活力也较低。冷暴露 ( 4℃ ) 1d后 ,血清T3与T4 浓度迅猛增长 ,随后 1～ 4周的冷驯化中 ,T3缓慢上升 ,T4 逐渐下降 ,肝脏和BAT的T4 5 脱碘酶活力变化与血清T3 和T3/T4 变化一致。表明冷驯化激活了甲状腺功能 ,激活了外周组织中的甲状腺激素代谢。
There were low serum T3 and T4 concentration and the activities of T4 5-deiodinase in liver and brown adipose tissue (BAT) in Mongolian gerbil(Meriones unguiculatus), at 22±2℃ of room. Serum T3 and T4concentration increased rapidly after cold exposure (4±2℃) for 1 day, both of which showed as 340% and 208% high , respectively, as those in warm. Following cold acclimation from 1 week to 4 weeks, serum T3 level rose slowly and T4 decreased slowly, leading to the increase of T3/T4. The changes in T4 5-deiodinase activities of BAT and liver were similar to those of serum T3 and T3/T4 during cold exposure. These results indicated that thyroid activity and the metabolism of thyroid hormone in peripheral tissue were activated by cold acclimation in Mongolian gerbil, which may take part in regulation of basal metabolic rate and nonshivering thermogenesis.
出处
《兽类学报》
CAS
CSCD
北大核心
2001年第2期132-136,共5页
Acta Theriologica Sinica
基金
国家自然科学基金!资助项目 (No . 396 70 12 2 )
国家教委博士点基金
