粘多糖累积症34例尿筛查分析

Analysis by urine of children with Mucoplysaccharidosis

目的 :探讨尿筛查对粘多糖累积症的辅助诊断价值。方法 :对 34例临床上初诊为粘多糖患儿采用溴化十六烷三甲基铵浊度实验和酸性白蛋白实验进行筛查。结果 :溴化十六烷三甲基铵浊度实验阳性率达 97.1% ,酸性白蛋白实验阳性率达 94.1%。结论 :尿筛查可辅助诊断粘多糖累积症 ,适宜推广应用。

Aim:To apply urinalysis technique to diagnosis for Mucopolysaccharidosis (MPS). Methods: The nexadecyltrimethylammonium bromide and acid albumin fraction experimental method was used for screening suspicious children with MPS. Results: The positivity rate of nexadecyltrimethylammonium bromide and acid albumin fraction were 97.1% and 94.1% respectively. Conclusion: The urinalysis technique is helpful for screening and diagnosing MPS.