Graves'眼病的放射治疗

Radiotherapy for Grave's Ophthalmopathy

目的 :分析 Graves'眼病的放射治疗疗效。材料与方法 :196 4年～ 1992年间收治 94例Graves'眼病患者 ,其中 90例为双侧突眼 ,4例为单侧病变。放疗剂量 9～ 2 5 Gy。结果 :总有效率为 83% ,眼睑水肿 ,眼痛等放疗后改善明显 ,特别是急性水肿和病程较短者效果更好。照射野包括垂体与否对疗效无明显影响 ,无明显副作用。结论 :放疗是 Graves'眼病有效的治疗方法 ,合并甲亢的 Graves'眼病放疗效果较差。放疗剂量 2 0～ 2 5 Gy/ 3周疗效较好。

Purpose: To review radiotherapy for Grave's ophthalmopathy. Materials and Methods: From 1964 through 1992, 94 patients with Grave's Ophthalmopathy (4 unilateral and 90 bilateral lesions) were treated by radiotherapy with the doses of 9～25Gy. Results: The overall effective rate was 83%. Edema of the eyelid , proptosis and ophthalmalgia were significantly improved. No complication of pituitary gland was found for patients whose pituitary glands were involved in the radiation ports. Conclusion: Radiotherapy is effective for Grave's Ophthalmopathy. The radiation dose advised is 20～25Gy/3wks.