鸢尾酮的合成研究

Synthesis of Irone

采用山苍子油提取得到的柠檬醛和丙酮等为主要原料合成鸢尾酮。合成分三步完成。先用柠檬醛与丙酮在碱的催化下生成假紫罗兰酮 ,收率为 93 .2 %。假紫罗兰酮甲基化生成假鸢尾酮 ,收率为 52 .3 %。假鸢尾酮环化得到鸢尾酮 ,收率为 98.3 %。合成的总收率较高达到 4 7.9%。并对合成的鸢尾酮进行了理化性质、光谱、色

Irone was obtained through three steps reactions with citral and acetone. Citral reacted with acetone in the base catalyst to give pseudoionone. The yield was 93.2%. After methylating, pseudoirone was prepared. The yield was 52.3%. Pseudoirone cyclized with mixed acid as cyclizing agent to give irone. The yield was 98.3%. The total yield was high to reach 47.9% and the reaction was easy to control. The product was determined by spectroscope, GC-MS, odor evaluation and so on.