人工授精后血小板计数变化在早孕诊断中应用价值的研究

Value of platelet count before and after artificial fertilization in early pregnancy diagnosis.

目的 :为探讨血小板计数法用于超早孕诊断的可行性和可靠性。方法 :对行AID术的健康妇女 5 8例和处于正常排卵期的未婚妇女对照组 2 8例 ,采用库尔特血细胞计数仪测量血小板数。结果 :5 8例AID妇女血小板下降者 34例 ,占6 4%。 12例化学妊娠者只有 1例血小板未下降 ;2 8例对照组未孕妇女中血小板下降者 3例。诊断敏感性为 91.7% ,特异性89 .3% ,阳性预期率 78.5 % ,阴性预期率 96 % ,诊断效率 90 0 % ,诊断指数 181%。结论 :测定授精后血小板计数变化 ,可简单快速地判断体内有无受精卵。

Objectve:The variation of platelet count before and after woment artificial fertilization(48hr) was studied to explore the feasibility and reliability of platelet count in diagnosis of pregnancy before implantation.Method:58 healthy women were subjected to artificial fertilization with 22 non-pregnant woment at the ovulation period as control.Platelet was conunted by COULTER blood cytometer.Results:A decrease in the platelet count was detected in 34 of 58 women through artificial fertilization, accounting for 64%,and 3 of 28 non-pregnant women. Only one of 12 pregnant women didn't have a decrease in the platelet count.The diagnosis had a sensitivity of 91.7%,specificity of 89.3%,positive predictive value of 78.5%,negative predictive value of 96%,diagnosis effeciency of 90.0% and diagnosis index of 181%.Conclusion It can be determined simply, quickly that ovum isn't fertilized in the body according to no decrease in the platelet count after fertilization with a reliability of 90.9%.