广东省1988-1998年流感流行与监测分析

Analysis on Influenza Epidemic and Surveillance in Guangdong between 1988 and 1998

[目的 ]了解广东地区流感流行情况 ,探讨流行特征 ,提供防治建议。 [方法 ]建立全省流感监测网 ,进行流行病学和病原学调查。 [结果 ]1988- 1998年流感流行高峰在每年的 3～ 7月 ,其中 7年流行优势毒株为 H3N2 毒株。由于发生明显的血清学抗原漂移 ,1996年 H3N2 毒株引起广东地区流感流行。 1998年禽流感监测中 ,从 9例患者流感鼻咽拭子中分离到 H9N2 流感毒株 ,与此同时 ,从鸡群分离到禽 H9N2 毒株。[结论 ]广东地区每年只有一个流感流行峰 ,目前 H3N2 流感毒株仍是广东地区的优势毒株 ,流感 H9N2 毒株对人类的致病性值得进一步探讨。

Objective] To investigate the epidemiological characteristics of influenza and provide the control measures [Methods] To establish the influenza surveillance network and investigate the influenza epidemic and pathogen [Results] The epidemic peaks were annually on March to July in Guangdong in 1988-1998,The epidemic in 7 years was predominated by H 3N 2 strain The outbreak of influenza occurred in 1996 because of the remarkable antigenic drift of H 3N 2 strain The H 9N 2 strains were isolated from 9 patients and the chicken in 1998 [Conclusion] There is one epidemic peak annually in the province The epidenic is predominated by H 3N 2 strain in Guangdong province.It is worth to research the pathogenicity of influenza H 9N 2 in the future.