摘要
目的··:研究海洛因依赖者脱毒前后外周血大颗粒淋巴细胞的变化。方法··:采用瑞氏 -姬姆萨染色法 ,检测54例海洛因依赖者脱毒前后外周血中大颗粒淋巴细胞所占的百分率。结果··:海洛因依赖者脱毒前总大颗粒淋巴细胞低于对照组 ,有非常显著性差异 (P<0.01) ;女性略高于男性无显著性差异 (P>0.05) ;脱毒后总大颗粒淋巴细胞高于对照组 ,有非常显著性差异 (P<0.01) ;女性明显高于男性 ,有非常显著性差异 (P<0.01)。结论··:海洛因依赖者脱毒后外周血大颗粒淋巴细胞显著增高 ,这可作为初步评价海洛因依赖者脱毒后自然免疫力状态的一项指标。
Objective: To study the change of the large granular lymphocytes(LGL)of periphery blood in heroin addicts. Method: The percentage of LGL in 54 patients before and after detoxification was detected by Wright and Gimsa stain. Result: The number of total LGL before detoxification was lower than that of control(P<0.01); and women 's LGL level was little higher than men's(P>0.05); the number of total LGL after detoxification was higher than that of control (P<0.01); and women's LGL level was much higher than men's (P<0.01).Conclusion: There is great change in the LGL level of drug addicts after detoxification, which could be an index to estimate preliminarily immune state in heroin addicts.
出处
《中国药物依赖性杂志》
CAS
CSCD
2001年第2期116-118,共3页
Chinese Journal of Drug Dependence
关键词
海洛因依赖
大颗粒淋巴细胞
免疫功能
heroin dependence
large granular lymphocyte
immunofunction