鲁南欣康、多巴胺治疗肺心病急性加重期84例

The treatment of 84 acute stage chronic cor-pulmonale with isosobide mononitrate and dopamine.

目的 观察鲁南欣康注射液与多巴胺联合治疗肺心病的结果。方法 对照组 80例给予抗生素、吸氧、纠正水电解质失衡、止咳祛痰等治疗。治疗组 84例 ,在上述治疗的基础上给予鲁南欣康 2 0mg +多巴胺 40mg +生理盐水2 0 0ml静脉滴注 ,1日 1次 ,疗程 10天。结果 治疗组总有效率 88 1% ,对照组 6 8 8% ,两组疗效差异显著 (P <0 0 1)。治疗组血液流变学各项参数改善明显 (P <0 .0 1或P <0 .0 5 ) ,而对照组变化不显著 (P >0 .0 5 )。治疗组PaO2 提高Pa CO2 降低 ,治疗前后有显著差异 (P <0 .0 1)。结论 鲁南欣康。

Objective TO observe the effect of isosobide mononitrate and dopamine on chronic cor pulmonale.Methods One hundred and sixty four cases of chronic cor pulmonale were randomly divided into treatment group(n=84)and control group(n=80).The control group was given antibiotics,oxygen,and treatments for expectoration,relieving cough and balancing hydro electrolytic disorder;the treatment group was given the above therapies and isosobide mononitrate 20mg + dopamine 40mg + NS200ml intravenously once a day for 10 days.Results Significant difference was seen in total efficacy between the treatment group (88.1%) and the control group (68.8%)( P <0.05);hemorrheology was improved in treatment group but not in control group;PaO 2 increased and PaCO 2 decreased in treatment group( P <0.01).Conclusion Isosobide mononitrate and dopamine are effective drugs for chronic cor pulmonale.