新生儿先天性梅毒的骨骼X线表现

Skeletal radiographic findings in neonates with congenital syphilis

目的 评价骨骼X线片在新生儿先天性梅毒诊断中的价值。方法 搜集 2 8例新生儿先天性梅毒的骨骼X线片 ,分析其表现。结果 2 8例中 2 6例有骨骼异常改变。先期钙化带增宽2 3例 ,先期钙化带呈锯齿状边缘 19例 ,先期钙化带下透亮带 2 6例 ,骨膜反应 6例 ,骨髓炎 5例。骨骼改变呈多发、对称、广泛性 ,多侵犯长骨 ,也累及不规则骨。结论 新生儿先天性梅毒骨损害出现率高 ,其X线表现具有特征性 ,可作为诊断手段。

Objective To evaluate the values of skeletal radiographs in diagnosing congenital syphilis in newborns. Methods Twenty eight bone radiographs were obtained for newborns with congenital syphilis and their abnormalities were analyzed. Results Bone radiographic abnormalities were identified in 26 of 28 cases. There were deepening or increase of the width of the provisional zone of calcification (23 cases), serrated appearances of the zone at the diaphyso epiphyseal junction (19 cases), lucent metaphyseal bands (26 cases), periosteal reactions (6 cases), and osteomyelitis (5 cases). The skeletal changes were multiple, symmetric, and extensive, and changes were also found in irregular bones besides long bone in most of cases. Conclusion There was high frequency of bone abnormalities in newborns with congenital syphilis. The bone radiographic findings were characteristic, and it could be served as means of diagnosing this condition. The irregular bones such as pelvis should also be included in radiographs.