摘要
目的 :探讨理气活血中药对应激大鼠免疫和血液流变性调整的作用机理。方法 :观察理气活血中药对应激大鼠血浆去甲肾上腺素含量、脾淋巴细胞增殖功能和血液流变性影响。结果 :疏肝理气、活血化瘀及理气活血中药 ,可不同程度对抗应激所致的变化 ,其中以理气活血中药的效果最好。理气活血中药可降低应激大鼠血浆去甲肾上腺素的含量 (P <0 0 1) ,调整外源性去甲肾上腺素大鼠的全血粘度 (P <0 0 5) ,提高脾淋巴细胞增殖功能 (P <0 0 1)。结论 :理气活血中药是通过降低去甲肾上腺素的含量而增强免疫功能 。
Objective: To explore the modulation effect of Chinese herbal medicines for Qi regulating and blood activating (QRBA) on mechanism of immunity and hemorrheology in stressed rats. Methods: The influence of QRBA on plasma noradrenaline (NA), proliferation of splenic cells and hemorrheologic properties were observed in stressed rats. Results: The Chinese herbal medicines for soothing Liver to regulate Qi, activating blood circulation to remove stasis and QRBA drugs could antagonize in various degrees the changes caused by stress. Amony them QRBA drugs was the best, it could reduce the level of plasma NA (P<0 01), modulate the blood hyper viscosity induced by exogenous NA (P<0 05) and enhance proliferation of splenic cells (P<0 01) in rats. Conclusion: QRBA drugs strengthen immune function and restore hemorrheologic properties by reducing NA content in organism.
出处
《中国中西医结合杂志》
CAS
CSCD
北大核心
2001年第5期364-366,共3页
Chinese Journal of Integrated Traditional and Western Medicine
基金
卫生部科研基金资助项目!(94- 1 - 2 77)
关键词
应激
免疫
血液流变性
理气活血中药
实验研究
stress, immunity, hemorrheologic property, Qi regulating and blood activating drugs
