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^(125)I巩膜敷贴器的剂量学特性的研究 被引量:8

Studies on characteristics of dosimetry for ^(125)I ophthalmic applicator
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摘要 用经验公式按合适的几何模型作剂量学计算 ,可以得到对应于不同的几何形状和不同放射源活度的等剂量曲线。用LiF热释光片在水 -有机玻璃体模及空气中 ,分别作12 5I眼科巩膜敷贴器的表面剂量测定 ,结果在误差范围内无明显区别 ,得到的最终表面剂量及其均匀性分别为 :( 3.4 6± 0 .0 1)、( 0 .178± 0 .15)nGy h·Bq。用BaF2 闪烁探测器及LiF热释光片分别作敷贴器正面、背面等的计数测量和剂量测定 ,得到12 5I巩膜敷贴器的剂量的空间分布 ,其中 ,背面剂量不到正面剂量的 0 .1%。用LiF热释光片在水 -有机玻璃人体模型中作沿着眼睛中心轴的深度剂量分布的实验测量结果表明 ,测量距离大于约 5mm以后 ,计算值与实验值在误差范围内完全符合 ;在距离小于约 5mm时 ,计算值明显高于实验值 。 Isodose curves for 125 I ophthalmic application in different geometry and activity can be obtained using the empirical formula based on suitable geometric model. The results of surface dose rate determined with lithium fluoride (LiF) thermoluminescent dosimeter (TLD's) chips in water-organic glass phantom and air had no obvious difference and the surface dose rate and its uniformity, (3.46±0.011) and (0.178±0.15)nGy/h·10 7Bq were obtained. Count measurements and dose determinations for the front and back etc. of the ophthalmic applicator with BaF 2 scintillation detector and LiF TLD's had revealed the space distribution of dose for 125 I ophthalmic applicator in which dose on the back was less than 0.1% of that on the front. The distribution of the absorbed dose rate along the eye axis had been measured using LiF TLD's in water-organic glass phantom. The measured and calculated dose data indicated that when measuring distances were larger than about 5mm the experimental results agreed with those from calculation within the range of error, otherwise the measured values were lower, still it could be explained by experimental conditions.
出处 《核技术》 CAS CSCD 北大核心 2001年第5期393-397,共5页 Nuclear Techniques
关键词 巩膜敷贴剂 剂量学 测量 计算 125 眼科疾病 放射治疗 I, Ophthalmic applicator, Dosimetry, Measurement, Calculation
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参考文献10

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共引文献4

同被引文献19

  • 1廖东声,谢元.非对称信息与会计舞弊——安然事件给我们的启示[J].华南农业大学学报(社会科学版),2003,2(z1):51-56. 被引量:2
  • 2蔡善钰,卢风才,王光璐,宋跃,黄朝阳,马凯,高雪松,杨隆艳,王海云.^(125)I巩膜敷贴器的研制与临床观察[J].中国原子能科学研究院年报,2004(1):141-142. 被引量:9
  • 3魏文斌.进一步提高我国脉络膜黑色素瘤的诊断治疗水平[J].中华眼底病杂志,2006,22(3):147-149. 被引量:30
  • 4王光璐,魏文斌,蔡善钰,卢凤才,马凯,李斌.脉络膜黑色素瘤敷贴放射治疗的初步观察[J].中华眼底病杂志,2006,22(3):157-160. 被引量:11
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