摘要
目的与方法 :采用蚕豆根尖微核试验技术对两种市售二氧化氯 (ClO2 )的诱变性进行研究。结果 :在ClO2 的稀释度为 1:10 0时 ,杭州产ClO2 (A样 )与余杭产ClO2 (B样 )蚕豆根尖细胞微核率 (MNF)分别为 (17.91± 4.80 )‰和 (17.5 7± 3.15 )‰。,与作为阴性对照的自来水相比较 ,均有显著的统计学差异 (P <0 .0 1) ,并呈现较强的剂量 反应关系。 结论 :消毒剂ClO2 能诱发蚕豆根尖细胞微核率的增加 ,具有一定的诱变性。
Purpose and Methods: The mutagenecity of two batches of chlorine dioxide(ClO\-2) were studide using micronucleus test in Vicia faba root tip cells. Results: The frequencies of micronucleus of two kinds of ClO\-2 were (17.91±4.80)‰ and (17.5±3.12)‰ respectively when the diluent multiple of ClO\-2 was at 1:100. Comparing with the tap water group, the differences(χ\+2\-A=30.57, χ\+2\-B=29.60 P<0.01) was statistically \{significant\} and the dose effect relationship ws clear. Conclusion: Clorine dioxide has mutagenicity. We should pay attention to safety of its apllication in food and water.
出处
《癌变．畸变．突变》
CAS
CSCD
2001年第2期98-101,共4页
Carcinogenesis,Teratogenesis & Mutagenesis
关键词
蚕豆
微核试验
二氧化氯
诱变性
Vicia faba
micronucleus test
chlorine dioxide
mutagenicity
