云南森林脑炎病毒的调查

Investigation of the Russian Spring-Summer Encephalitis Virus in Yunnan Province

通过 1988～ 1994年对云南森林脑炎病毒流行病学调查、病毒的普通生物学及分子生物学特性研究 ,首次发现云南高黎贡山存在森林脑炎病毒的自然疫源地 ,经病毒分离及血清学检测 ,推测卵形硬蜱为其主要传播媒介 ,鼠类动物为其主要贮存宿主。对人可引起高热、皮疹等全身感染症状。云南森林脑炎病毒与东北森林脑炎病毒相比较 ,云南毒株毒力稍低 ,对各种动物的致病性相似 ,但又有明显的出血现象。血凝的最适pH基本一致。云南森林脑炎病毒与东北标准株的多肽成分分析略有不同。云南高黎贡山的自然地理景观与东北大小兴安岭的地理景观不同 ,这与其毒株之间的差异可能有关。血清学调查显示云南大部分地区可能存在森林脑炎病毒。

The Russian spring_summer encephalitis virus(RSSEV) of Yunnan was investigated in 1988～1994 in Gaoligongshan mountain,Yunnan.Its main vector is ixodex ovatus.Its main host is rodents.The main symptom of RSSEV is hige_fever、rash and so on.The toxicity of the RSSEV is lower than the virus of northeast in China.The RSSEV's symptom for some animals is similar with the northeast RSSEV,but the RSSEV of Yunnan has haemorrhage symptom,such as rash.Their red cells agglutinated pH are similar.there are a bit different in the polipeptide analysis between the RSSEV and the northeast RSSEV.The antibodies against the RSSEV are positive in the most areas of Yunnan.