原发性食管恶性黑色素瘤(附3例报告)

Primary Malignant Melanoma of the Esophagus (Three Cases Report)

原发性食管恶性黑色素瘤罕见。本文报告3例,其发生率为0.05％(3/6126)。其术前确诊困难,食管镜检查发现褐色新生物应警惕为食管恶性黑色素瘤。其恶性度高,常早期血行转移,预后较差。本组无长期生存者,其中1例给予术后化疗,无明显效果。本文结合文献就其发生率、组织病理学诊断标准、治疗及预后进行了讨论。

Primary malignant melanoma of the esophagus is rare. Three cases of this disease were reported in this article. The incidence was 0. 05% (3/6126). To establish the diag-nosis preoperatively is difficult,but if the brown neoplasma was ohservcd through esophagoscope malignant melanoma should be suspected. Because this tumor is higher malig-nance and easy tohematogcnous metastasis the prognosis us poor. No one obtained long time survive in our guoup. Though one case was given chemotherapy after resection, there was no obvious sesponse. In this article the incidince, histodiagnostic standard, management and prognosis were discussed with review of lite literatures