摘要
目的 为了解良性前列腺增生 (BPH)患者产生下尿路症状的成因 ,为正确诊治下尿路症状提供准确的证据。 方法 采用尿动力学方法分析无神经系统疾病的良性前列腺增生患者的膀胱尿道功能。 结果 16 4例良性前列腺增生患者 ,平均年龄 6 7± 7 0 4岁 ,膀胱出口梗阻者占 6 1 6 %(10 1/ 16 4) ,无梗阻者占 38 4% (6 3/ 16 4) ;逼尿肌收缩力正常者为 83% (136 / 16 4) ,逼尿肌收缩力减弱者17% (2 8/ 16 4) ,以上各组之间I PSS评分和年龄无显著性差异。膀胱出口无梗阻者中逼尿肌收缩力减弱者占 44 4% (2 8/ 6 3) ,逼尿肌收缩力正常占 5 5 6 % (35 / 6 3)。在膀胱出口无梗阻者中 ,逼尿肌收缩力减弱合并不稳定膀胱患者为 2 8 6 % (8/ 2 8) ,而逼尿肌收缩力正常合并不稳定膀胱患者 5 7 1% (2 0 /35 ) ,膀胱出口无梗阻逼尿肌收缩力减弱合并不稳定膀胱患者明显少于膀胱出口无梗阻逼尿肌收缩力正常者 (P <0 0 2 ) ,两组患者I PSS评分和膀胱顺应性均无明显差异。 结论 BPH患者下尿路症状的产生不仅与前列腺增生引起的膀胱出口梗阻有关 ,部分患者并不存在膀胱出口梗阻 ,其下尿路症状的成因为逼尿肌功能变化所致 。
Objectives To understand the causes of lower urinary tract symptoms(LUTS) of patients with benign prostate hiperplasia (BPH), and to provide more convinced evidences for treatment of those patients with LUTS. [WT5”HZ]Methods[WT5”BZ] Patients with BPH and without any other diseases which might affect detrusor function were evaluated with urodynamics. [WT5”HZ]Results[WT5”BZ] One hundred sixty four patients with BPH were included in this study. 101 (61 6%) patients with BPH diagnosed routinely had bladder outlet obstruction(BOO) and 63 (38 4%) had no BOO. No statistically significant differences of I PSS and age were observed between the two groups. 136 (83%) patients with BPH had normal detrusor contractility and 63 (17%) had decreased detrusor contractility; there was also no any significant differences of I PSS and age between the two groups. In the 63 patients without BOO, 28 (44 4%) patients had decreased detrusor contractility and 35 (55 6%) had normal contractility. The incidence of bladder instability was 28 6% in non BOO and decreased detrusor contractility patients. It was lower than 57 1% of those non BOO and normal detrusor contractility patients( P <0 02). There were no significant differences of I PSS and bladder compliance between the two groups. [WT5”HZ]Conclusions[WT5”BZ] The causes of LUTS of patients with BPH are associated not only with BOO caused by BPH, but also with disarrangement of detrusor function for those BPH patients without BOO. Urodynamcs could provide more convinced evidences for treatment of patients with LUTS.
出处
《中华外科杂志》
CAS
CSCD
北大核心
2001年第4期299-301,共3页
Chinese Journal of Surgery
关键词
前列腺增生
肌收缩
尿动力学
BPH
Prostatic hyperplasia
Muscle contraction
Urodynamics