肝硬化患者空腹胃动力障碍的临床研究

Clinical study on fasting gastric dysmotility in patients with liver cirrhosis

目的 :探讨肝硬化患者胃动力障碍发生率及其与肝功能的关系。方法 :运用体表胃电图观察 58例肝硬化患者和 2 2例健康人空腹胃肌电活动情况 ,观察指标包括平均振幅 ( AP)、平均过零频率 ( FZ)、中心频率 ( FC)、主频 ( FP)以及频谱形态。结果 :肝硬化患者胃电节律紊乱率明显高于健康组 ,其中 FZ分别为 38%和 50 % ;FP分别为 57%和 50 % ;Child- Pugh A组胃窦电节律紊乱率在 FP、FZ分别为 4 0 %和 2 0 % ;Child- Pugh B组分别为 61%和 32 % ;而 Child- Pugh C组则 10 0 %有胃窦节律异常。结论 :肝硬化患者电节律紊乱率较正常人明显升高 。

Objective:To investigate the relation between gastric dysmotility and liver function in patients with liver cirrhosis.Methods:With the help of electrogastrography (EEG),several indications,including the mean amplitude (AP),frequency over zero (FZ),central frequency (FC),primary frequency (FP) and the shape of frequency spectrum,were observed in fifty eight patients with liver cirrhosis and twenty two healthy subjects.Results:The rate of electrogastric dysrhythmia was much higher in patients with liver cirrhosis than in healthy group,FZ being 38% and 50%,FP 57% and 50%,respectively;FP and FZ of gastric antrum was 40% and 20% respectively in Child Pugh A group,61% and 32% respectively in Child Pugh B group;and the rate of gastric antrum dysrhythmia was 100% in Child Pugh C group.Conclusion:The rate of eletrogastric dysrhythmia is much higher in patients with liver cirrhosis than in healthy group,and liver function had an effect on electrogastric rhythm. [