动物大肠杆菌耐药性的变化趋势

Changes of Antimicrobial Resistance of E.coli

本试验对 50年代至 90年代初分离保存的 50株大肠杆菌进行了药物敏感性测定。结果表明 ,随着时间的推移 ,菌株对 1 5种抗菌药物的耐药性呈现不同程度的上升趋势 ,50年代的大肠杆菌分离株对 1 5种抗菌药物均敏感 ,60年代的分离株对链霉素、四环素产生耐药 ,70年代对氨苄西林、氯霉素、磺胺甲基异唑、四环素、链霉素、甲氧苄胺嘧啶 6种抗生素产生耐药 ,80年代至 90年代初对阿莫西林 /奥格门丁、庆大霉素、卡那霉素、萘啶酸、头孢噻吩、氨苄西林、氯霉素、磺胺甲基异噁唑、四环素、链霉素、甲氧苄胺嘧啶 1 1种抗生素产生耐药 ,菌株的多重耐药性呈上升趋势。

strains of E.coli isolated from 1950s' to 1990s' times were studied for antimicrobial susceptibility in this report. The result shows that the rates resistance is increasing.The strains of isolated from 1950s' are all susceptible. The strains of 1960s' are resistant to Tetracycline and Streptomycin,The strains of 1970s' are resistant to Ampicillin, Chloramphenicol, Sulfamethoxazole, Trimethoprim, Tetracycline and Streptomycin .The strains of 1980s'and early 1990s' are resistant to Amoxicillin/Clavu, Cephalothin, Gentamicin, kanamycin, Nalidixin Acid Ampicillin, Chloramphenicol, Sulfamethoxazole, Trimethoprim, Tetracycline and Streptomycin.There are a significantly increasing tendency of multi resistance.