肝癌的冷冻外科治疗

Cryosurgery for Liver Cancer

[目的]探讨冷冻治疗肝癌的方法、疗效及安全性。[方法]应用LSC 2000型冷冻机对72例肝癌分别采取开腹冷冻、经皮穿刺冷冻及腹腔镜下冷冻治疗。[结果]全组无手术死亡 ,无出血、肝破裂、胆漏及穿刺道种植转移等并发症 ;65例冷冻前AFP增高 ,50例冷冻后有不同程度下降 ,11例降至25ng/L以下 ;冷冻后1、2、3年生存率分别为69 2 %、53 8 %、43 1 % ,其中17例≤5cm的小肝癌则分别为88 2 %、76 5 %、64 7 %。[结论]冷冻为不能手术切除的肝癌提供了一有效的治疗途径 ;经皮穿刺或腹腔镜下冷冻治疗肝癌是一种安全、有效、微创的治疗新方法。

To evaluate the method,effect and safety of cryosurgery for primary and metastatic liver cancer.Seventy two patients with liver cancer were treated with LSC 2000 system by open cryosurgery,percutaneous cryosurgery and laparoscopic cryosurgery.There were no operative mortality and no severe complications.The overall 1 ,2 and 3 year survival rates were 69 2%,53 8% and 43 1% respectively,and those in patients with small liver cancer (≤5cm) were 88 2%,76 5% and 64 7% respectively.[Conclusion]Cryosurery offers an effective approach for unresectable liver cancer,and percutaneous cryosurgery or laparoscopic cryosurgery is a safe,effective and minimum invasive method.