摘要
采用火焰原子吸收光谱法检测了急性脑梗塞病人血清总铁（Fe）含量，同时测定了患者血清丙二醛（MDA）含量和超氧化物歧化酶（SOD）活性．结果，急性脑梗塞病人血清Fe含量显著升高（P<0.01），血清MDA含量显著升高（P<0．01），血清SOD活性显著下降（P<0.01）．提示，铁、自由基参与了急性脑梗塞的病理生理过程.
In order to investigate the pathogenesis of ischemic brain damage, the serum in Fe levels 100 cases of acute cerebral infarction (ACI) and 50 control subjects were measured by flame atomic absotption spectrum. We also determined the MDA and SOD levels in serum of all subjects. The results show that Fe levels in serum of paticnts with ACI were significantly hgler than those of the control (P<0.01).Positive correlation between serum Fe and MDA levels was confirmed (P<0.01), while negaive correlation between serum Fe and SOD levels was found (P<0.05). It is suggested that Fe and free radicals are participated in the pathogenesis ofcerebral infarction.
出处
《黑龙江医药科学》
1999年第5期9-9,共1页
Heilongjiang Medicine and Pharmacy
