缺血性脑血管病患者红细胞免疫粘附功能的变化

Changes of red cell immune adherence in patients with ischemic cerebrovascular disorders

目的探讨缺血性脑血管病患者红细胞免疫粘附（ＲＣＩＡ）功能的变化。方法测定２０例短暂性脑缺血发作（ＴＩＡ）和５０例脑梗塞患者的红细胞Ｃ３ｂ受体花环率（ＲＢＣ－Ｃ３ｂＲＲ）和红细胞免疫复合物花环率（ＲＢＣ－ＩＣＲ）。结果缺血性脑血管病各组ＲＢＣ－Ｃ３ｂＲＲ与正常对照组相比显著降低，脑梗塞组ＲＢＣ－ＩＣＲ显著增高，急性期变化尤著（Ｐ＜０．０１）。

Objective To evaluate the functional change of red cell immune adherence(RCIA) in patients with ischemic cerebrovascular disorders(ICVD).Methods The contents of RBCC3bRR and RBCICR were determined in 20 cases of TIA and 50 cases of cerebral infarction.Results RBCC3bRR decreased significantly in all patient groups,while RBCICR increased significantly in cerebral infarction patient groups,the change of the acute stage was more significant(P<0.01).Conclusion There were a close relationship between RCIA function and occurrence and development of ICVD.