摘要
新生血管的形成是许多眼底疾病的一个共同环节。视网膜色素上皮(RPE)与新生血管的发生有着密切的关系。通过阐述视网膜色素上皮对新生血管发生的4个步骤,即血管外膜的降解、血管内皮细胞的迁移、血管内皮细胞的增生及新生血管成熟等的影响,回顾了视网膜色素上皮在眼底新生血管发生中的作用。阐明其在何种情况下促进新生血管的发生,或何种情况抑制新生血管的发生。
eovascularization is a common abnormality in ocular fundus diseases.The effects of retinal pigment epithelium(RPE)on the four steps of angiogenesis(degeneration of basement membrane,migration and proliferation of vascular endothelial cells,and formation of capillary tubes)were reviewed.The elucidation of the roles that RPE played in angiogenesis at different conditions may result in new ways to treat neovascularization.
出处
《眼科研究》
CSCD
1998年第2期155-157,共3页
Chinese Ophthalmic Research
关键词
视网膜色素上皮
新生血管
眼底病
RPE
etinal pigment epithelium neovascularization ocular fundus disease