卡介苗素注射液对反复呼吸道感染患儿免疫状态的影响

Influence of vaccine injection on Immunity of recurrent respiratory tract infectious children

目的 探讨卡介苗素注射液对反复呼吸道感染患儿免疫状态的影响。 方法 将 76例反复呼吸道感染患儿随机分为治疗组与对照组 ,治疗组用卡介苗素注射液治疗 ,同时用抗生素或抗病毒药物及对症治疗。对照组不用卡介苗素 ,其他治疗同前 ,观察疗效及治疗前后血清SIL 2R水平 ,IgG、IgA、IgM变化及PHA反应强度。 结果 应用卡介苗素治疗组总有效率达97 5 % ,与对照组比较 ,差异非常显著 ,P <0 0 1。治疗组SIL 2R水平明显下降 ,IgG水平提高 ,PHA皮试反应明显增强。 结论 卡介苗素注射液具有提高和调整细胞免疫和体液免疫功能的作用 ,可用来防治小儿反复呼吸道感染

Objective To explore influence of vaccine injection on immunity of recurrent respiratory tract infectious children.Methods We randomly divided the 76 cases into therapy group and control group.We used vaccine injection in therapy group,added with antibiotics,anti virus and treated corresponding diseases.While the control group was similar to the therapy group,in addition to no using vaccine injection.We observed the effect of treatment,the level of SIL 2R in the serum,changes of IgG,IgA,IgM and reaction intensity of PHA.Results Efficient rate of the therapy was 97 5%.The difference between two groups was very striking ( P <0 01).The level of SIL 2R evidently descended,while the level of IgG ascended,and skin test of PHA also was built up..Conclusion Vaccine injection boosted and improved cell immunity and fluid immunity.It might defend and treat RRI.