2Hopkins DF, Williams G. Insulin receptors are widely distributed in human brain and bind humans and porcine insulin with equal affinity [J].Diabetd, 1997,14(12) : 1044-1050.
3Kar S,Seto D,Dore S,et al.Insulin-like growth faetor-Ⅰ and Ⅱ differentially regulate endogenous acetylcholine release from the rat hipp-pocampal formation[J] .Proc Nail Acad Sci USA, 1997,94(25) : 140-144.
4Anlar B, Sullivan KA, Feldman EL. Insulin-like growth factor-Ⅰ and central nervous system development [.l]. Horm Metab Res, 1999, 31(2) : 120-125.
5Mc Call AL.The impact of diabetes on the CNS[J] .Diabetes, 1992,41(8) :557-560.
6Kanaka M, Sawade M, Miura M, et al. Insulln-like growth factor-1 aralogue preveuts apoptosis mediated through an interleukin-1 B converting enzyme(easpse-Ⅰ)-like protase of eerebellar development stage-specific mechanisms of neuronal all death [ J ]. Neurosci, 1998,84( 1 ) : 89-93.
7Tallroth G, Ryding E, Agardh C, et al. Regiomal cerebral blood flow in normal man during insulin-induced hypoglycemia and in the recovery period follwing glucose infusion [ J ]. Metab Clin Exp, 1992,41 ( 10 ) :717-721.
8Hamilton M, Tranmer B, Auer R. Insulin reduction of cerebral infarction due to transiont to focal ischemia [J]. J Neurosurg, 1995,82 (2) : 262-268.
9Shuaib A, Ijaz M, Wagar T, et al. Insulin elevates hippocampal GABA levels during ischemia: This is independent of its hypoglyamia effect[J]. Neurosci, 1995,67(4) :809-812.
10Tagami M, Yamagata K, lkeda K, et al. Genetic Vulnerability of cortical neurons isolated from stroke-prone spontaneously hypertensive rats in hypoxia and oxygen reperfusion [J ] . Hypertens Res, 1999,22 ( 1 ) :23-25.