摘要
本文研究了2-噻吩磺酰胺(Ⅰ)与草酰氯(Ⅱ)的反应,结果表明:无碱催化下(Ⅰ)与(Ⅱ)反应可生成2-噻吩磺酰异氯酸酯(Ⅲ),根据反应摩尔比的不同将同时生成N,N′-二-2-噻吩磺酰草酰胺(Ⅴ)或2-噻吩磺酰草氨酰氯(Ⅳ)。在吡啶催化下,反应主要生成N,N′-二-2-噻吩磺酰乙二酰脲(Ⅵ)或(Ⅲ)与2-噻吩磺酰氯(Ⅶ)的混合物;讨论了反应可能的机理;确定了用该反应合成2-噻吩磺酰异氰酸酯的较佳条件。
The reaction of 2-thiophene sulfonamide with oxalyl chloride has been investigated. The uncatalyzed reaction produced 2-thiophenesulfonyl iso cyanate and 2-thiophenesulfonyloxamide or 2-thiophenesulfonyloxamoyl chloride depending on the mole ratio of reactanta. In the presence of pyridine catalyst,however,the major product wao 2-thiophenesulfonylparabanate or mixtures of 2-thiophenesulfonyl isocyanate and 2-thiophenesulfonyl chloride. Probable mechanism of the reaction was discussed. About the optimun conditions for the synthesis of 2-thiophenesulfonyl isocyanate were determined.
出处
《华中师范大学学报（自然科学版）》
CAS
CSCD
1991年第4期439-442,共4页
Journal of Central China Normal University：Natural Sciences
基金
湖北省自然科学基金
关键词
噻吩磺酰胺
草酰氯
除草剂
2-thiophenesulfonamide
oxalyl ehlorcde
2-thiophenesulfonyl isocyanate
