异丙酚治疗安氟醚麻醉后躁动

Propofol reduces restlessness during recovery after enflurane anesthesia

目的 观察异丙酚治疗安氟醚麻醉后苏醒期躁动的疗效 .方法 选择 40例开胸行肺或食道手术患者 ,术中用安氟醚吸入麻醉 .术毕回麻醉 ICU全部麻醉未醒 .随机分两组 ,异丙酚组 2 5例给予异丙酚镇静 3h;对照组 15例让其自然苏醒 .结果 异丙酚组患者苏醒前后心率、血压无统计学差异 ,躁动发生率 8% (2 / 2 5 ) ;对照组患者苏醒时心率及血压较麻醉未醒时显著升高 (P<0 .0 5 ) ,躁动发生率 6 0 % (9/ 15 ) .结论 异丙酚显著降低安氟醚麻醉后躁动的发生率且血流动力学稳定 。

AIM To observe the effect of propofol on treating the restlessness post enflurane anesthesia. METHODS Forty patients who underwent lungs or esophagus operation were selected. Inhalation anesthesia with enflurane was used during the procedure. All patients were sent into ICU after the operation. Twenty five cases received propofol sedation in propofol group, the other fifteen recovered naturally in control group. RESULTS There was no difference between before and after recovery period from anesthesia with HR and MAP in propofol group. Restlessness occurred in two patients. The incidence rate was 8% (2/25). Compared with the baseline values before recovery, the HR and MAP in creased obviously during recovery in control group ( P < 0.05). Restlessness occurred in nine cases . The incidence was 60% (9/15). CONCLUSION Propofol obviously decrease the incidence of restlessness caused by enflurane postoperatively. The hemodynamics are stable.