保健食品中吡啶甲酸铬的检测方法研究

Study on the determination method of chromium picolinate in health food

为建立保健食品中吡啶甲酸铬的高效液相色谱分析方法 ,研究了提取方法和色谱柱、流动相等液相色谱分析条件的选择 ,并对其稳定性进行了长期试验。加标回收率 >93% ,相对标准偏差3 1,最小检出量 10 0mg kg ,结果符合保健食品分析的要求 ,可以用于片剂、胶囊等类型保健食品中吡啶甲酸铬的分析。

For developing the determination method of chromium picolinate in health food by HPLC,extraction method and HPLC operation conditions such as columns,mobile phase had been optimized.Long term stability test of chromium picolinate had been done.Recovery of the standard spiked >93%,the RSD was 3 1,the lowest detection limit was 10 0 mg/kg,the result fits the demand of the analysis of health food.This method can be used in analysis of the content of chromium picolinate in types of tablet and capsule health food.2 years store experiment in room temperature showed that chromium picolinate was stable. Author's address: Yang Dajin,Institute of Food Statety Control and Inspection,Ministry of the Health,Beijing 100021 PRC.