二异氰酸甲苯酯对工人危害的调查

HAZARDOUS EFFECTS OF TDI EXPOSURE

为保护工人健康于1984年8月对大连市二异氰酸甲苯酯(TDI)生产及使用厂进行了流调.接触组117人,对照组82人。调查结果表明:车间内此种毒物浓度在0.2mg/m^3左右的情况下,接触者可出现损害作用.其表现如下:(1)原发刺激作用表现为呼吸道刺激的症状和体征;(2)变态反应(IgE明显增高);(3)肝大、轻度肝功能异常;(4)神衰症候群、膝反射减弱及脑电图改变;(5)肺活量降低.

An epidemiological investigation was made for workers exposed to TDI. Among them, 117 workers were selected as exposed group and 82 workers as control group. Results showed that with the toxicant concentration of about 0.2 mg/m3 in the workshops, determental effects may be seen in the exposed workers. Its manifestations are as follow: (1) symptoms of respiratory stimulation and physical signs; (2) allergic reaction (significantly increased IgE) ; (3) hepatomegaly with mild hepatic dysfunctions (4) neurasthenic syndrome, knee reflex weakened and some changes in electroencephalogram) (5) lowered vital capacity.