围手术期腹腔化疗的合理性——附35例临床分析

The rationality of abdominal chemotherapy of perioperative period.Clinical analysis of 35 cases.

目的 探讨围手术期腹腔化疗对提高进展期胃肠道恶性肿瘤疗效的方法。方法 应用腹腔内化疗的方法对 35例中晚期胃肠道癌行术前、术中及术后的早期化疗。结果 全组病人均接受围手术期腹腔化疗 ,治疗后 1、2年生存率分别为 97.1%和 90 .9% ,肝转移率 0 % ,腹膜转移率 2 .86 %。结论 腹腔化疗对进展期胃肠道癌术后的治疗能明显提高生存率 ,减少腹腔转移率 ,方法简便易行安全 。

Objective Approach heighlening the therapeutic effectiveness of perioperative abdominal chemotherapy on advanced malignant tumors of gastrointestinal tract.Methods Applied early abdominal chemotherapy to 35 cases of infermediate late gastrointestinal carcinoma preoperatively, operatively and postoperatively.Results All the subjects of the group received the perioperative chemotherapy; and in one year or two after that, their respective survival rates are 97.1% and 90.9% with liver transfer rate (0%) peritoneum (2.8%).Conclusions Abdominal chemotherapy for advanced postoperative gastrointestinal carcinoma can remarkably improve the survival rate, reduce abdominal transfer rate; thus being a handy and safe method with mild toxic reaction.