溃疡型食管癌单纯放疗与综合治疗的临床观察

Radiotherapy alone and combination therapy for ulcerative esophageal carcinoma.

目的 了解溃疡型食管癌单纯放疗和综合治疗的区别。方法 对本院 1994.1～ 1998.12资料完整的 32例溃疡型食管癌 (单纯放疗组 18例 ,综合治疗组 14例 )进行回顾性分析。结果 两组的近期疗效 (CR+ PR)分别为 88.9%和 85 .7% ,P>0 .0 5。综合治疗组的消化道反应和白细胞减少多于且重于单纯放疗组 ,P<0 .0 5 ;平均治疗时间为 78天 ,长于单纯放疗组 (6 5天 ) ,P<0 .0 5。结论 单纯放疗组较综合治疗组有治疗反应轻 ,患者易于耐受 ,治疗时间短 。

Objective To compare radiotherapy alone and combination therapy for ulcerative esophageal carcinoma. Methods 32 patients with such cancer treated from January 1994 to December 1998 were analysed, including radiotherapy alone (R group) 18, combination therapy(chemotherapy plus radiotherapy, C+R group)14. Results CR+PR for the two groups were 88.9% and 85.7%, P>0.05. In C+R group, the gastroenteric adverse effects and leukopenia were more and severer, P<0.05, and the average time of treatment was longer than that of R group, P<0.05. Conclusions Radiotherapy alone was of less adverse effects, better patients' endurance, shorter course of treatment and less cost.