甲状腺未分化癌疗效及预后因素分析(附23例报告)

The analysis of the effect and responds of cure in the treating thyroid undifferentiated carcinoma 23cases report

目的 从影响甲状腺未分化癌疗效及预后的因素探讨早诊早治和合理的综合治疗。方法 甲状腺未分化癌 2 3例 ,男 11例 ,女 12例 ,最小年龄 40岁 ,最大年龄 82岁 ,平均 5 7.17岁。病史最长 37年 ,最短 15天。其中颈部肿物 19例 ,有浸润症状如声音嘶哑、呼吸困难、吞咽困难 10例。以单纯手术 ,手术加放疗 ,手术残留而放疗 ,姑息治疗四种方法进行。结果 1、2、3、5、10年生存率分别为 6 0 .8%、39.1%、30 .4%、13%、8.6 %。结论 治疗预后与原发灶、转移淋巴结大小及治疗方法的选择有密切关系。所以 。

Objective In this article we will evaluate the diagnosis and the treatment of thyroid undifferentiated carcinoma in early stage and its synthesized treatment by retrospecting the defective cause in the treatment.Methods We received and treated 23 individuals of thyroid undifferentiated carcinoma- 11 males, 12 females. And the age ranged from 40 to 82 years, the average is 57.17 years; the course ranged from 15 day to 37 years. In these subjects, 19 cases came to hospital beause of the lump in neck, 10 cases for the invading symptoms(such as hoareness, dyspnea, and dysphagia). We deal with the patients with four methods: single operation, operation plus radiation, post operation radiation for residue and palliative treatment.Results The proportion of survive of 1 year was 60.8%, 2 years 39.1%, 3 years 30.4%, 5 years 13%, 10 years 8.6%.Conclusions We recognized that the diametres of the primary foci, metastatic lymphonode, and the treatment methods are closely correlated with the prognosis, diagnosis and start treating in early stage and synthesized treatment are very important.