摘要
目的:建立高效液相色谱法测定恶丙嗪片含量的方法.方法:色谱柱: DiamonsilC18(200 × 4.6mm, 5μm),流动相:甲醇水(80: 20),检测波长:285nm.结果:恶丙嗪线性范围5~45μg/ml,回归方程为C=0. 0624A+45. 229r=0.9999,回收率为99.86%,日内精密度为RSD=0.92%,日间精密度为RSD=1.64%结论:方法准确、快速、简便.
Objective: To study high performance liquid chromatography for the determination of oxaperozin tablets. Methods: Diamonsil C18(200 × 4.6nun, 5μm) column was used, mobile phase was MeOH-water (80:20), and detection wavelength was 285nm. Results: Over the concentration range of 5-45μg/ml, the linear regressin equation was C=0.0624A+45.229, r=0.9999. The average recovery was 99.86%, The within-day RSD=0.92%. Conclusions: The method is found to be accurate.
出处
《黑龙江医药科学》
2001年第2期16-16,共1页
Heilongjiang Medicine and Pharmacy
关键词
高效液相色谱法
恶丙嗪
含量
测定
high performance liquid chromatographic
oxaprozin
determination