5-四氢呋喃基呋喃的合成

A Facile Synthesis of 5-Tetrahydrofuranylfuran

六碳醛糖与1,3—双酮或β-酮酸酯在氯化锌存在下缩合,再经酸性条件下环化生成50—60%得率的5-四氢呋喃基呋喃类化合物.

Condensation of aldehyde sugars with β-keto ketones or β-keto esters in thepresenoe of C.P.grade ZnCl_2 followed by acidic treatment yielded 5-tetrahydrofu-ranylfurans in good yields.