Ce^(3+)对细胞膜电位的影响

Effect of Ce^(3+) on membrane potential of cells

采用显微荧光术研究了 Ｃｅ３＋对肝细胞和 Ｖ７９细胞质膜电位和线粒体膜电位的影响。结果表明，低浓度的 Ｃｅ３＋降低肝细胞的质膜电位，高浓度则显著降低肝细胞的质膜电位，提示 Ｃｅ３＋可使细胞质膜通透性增加；Ｃｅ３＋可增加 Ｖ７９细胞线粒体膜电位，提示 Ｃｅ３＋可增加细胞的能量供应。

The effect of Ce3+ on plasma membrane potential and mitochondrial membrane potential of bepatocytes and V79 cells was studied with microfluorometry. The results showed that Ce3+ could increase the plasma potential of hepatocytes in low dose and increase the plasma potential of hepatocytes in high dose significantly. The results the showed that Ce3+ could increase the mitochondrial membrane potential of V79 cells. The results suggested that Ce3+ could enhencl the permeability of plasma membrane and increase the energysupplying of cell