单侧迷走神经支配下胃动力的实验研究

Experimental study of single vagus on gastric motflity

目的 探讨家兔单侧迷走神经对胃动力指数的支配影响。方法 选用12只健康成年家兔,全麻下将测压导管插置于胃窦内,分别以电刺激兴奋双侧迷走神经干、左侧和右侧迷走神经干,测量三种不同状态下胃蠕动频率及蠕动波压力,并进行相互间比较。结果 单独左、右迷走干兴奋时胃动力指数分别占双侧迷走干兴奋时胃动力指数的69％(0.69±0.22)和22％(0.22±0.20),左迷走干兴奋时胃蠕动功能高于右迷走干兴奋时的胃蠕动功能,并高于基本胃蠕动功能标准。结论 左迷走干是影响胃动力的优势干,食管癌切除术中只要保留左迷走神经干,即可望获得满意的胃动力。

Objective To observe the effect of single vagus on gastric motility. Methods With 12 healthy adult rabbits, after they were anaesthetized, we put a pressosensitive tube into their gastric antrums, the vagus was excited by electricity. When both vagus excited, only a left vagus excited, and only a right vagus excited, the frequency and pressure of gastric peristaltic waves were measured. Then, we compared the gastric peristaltic function in three different phases. Results When only a left vagus excited, or only a right vagus excited, the index of gastric motility accounted respectively for 69% (0.69±0.22) and 22%(0.22±0.20) of that during both vagus excited. When only a left vagus excited, the gastric function was higher than that during only a right vagus excited, and it was higher than the primary standard of gastric peristaltic function. Conclusion The left vagus is superior in effect on gastric motility. In the esophagectomy, if single left vagus is preserved we may still get a satisfied gastric motility.