颅脑创伤急性期外周血白细胞变化的临床意义

Changes and its clinical significance of acute peripheral white blood cell in acute traumatic craniocerebral injury

目的 探讨颅脑创伤急性期外周血白细胞 (PWBC)数及中性粒细胞 (PMN)比例与病情及预后的关系。方法 回顾性分析总结 5 0例颅脑创伤急性期外周血白细胞数及中性粒细胞比例 ,根据病情或预后分组分别进行比较。结果 颅脑创伤病情重者较病情轻者PWBC数与PMN比例显著增高 (P <0 0 5 ,P <0 0 0 1) ;恢复不良组及死亡组与恢复良好组相比 ,PWBC数显著增高 (P <0 0 5 ,P <0 0 1)。结论 临床监测PWBC数及PMN比例可作为颅脑创伤患者的病情判断和预后估计的一项辅助指标。

Objective To evaluate the relation of acute peripheral white blood cell(PWBC)count and polymorphonuclear cell(PMN)proportion with the severity of traumatic brain injury(TBI)and the prognosis of TBI.Method The clinical data of 50 TBI cases were analysed retrospectively.The cases were divided into groups according to the severity of injury of the prognosis,and the PWBC counts and PMN proportions were compared among the groups.Result PWBC counts and PMN proportions were higher in the group of severe TBI than in the groups of mild or moderate TBI(P<0.05,P<0.001).PWBC counts were higher in the groups of poor prognosis and death than in the groups of good prognosis(P<0.05,P<0.01).Conclusion PWBC count and PMN proportion are useful clinical tools to predict the severith and prognosis of TBI.