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S-腺苷甲硫氨酸的临床及药理研究进展 被引量：30

The Development of Clinical and Pharmacological Study on S Adenosyl L methionine
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摘要 综述一种重要的内源性物质 S-腺苷甲硫氨酸及其代谢物的生化及药理作用 。 The biochemical and pharmacological aspects of the important endogenous molecule S Adenosyl L methionine (SAMe) and its metabolites were reviewed. The current clinical applications of SAMe as well as its clinical potential were also introduced.
作者 杨静 王旻 韦平和
机构地区 中国药科大学生物制药学院
出处 《药学进展》 CAS 2001年第3期164-167,共4页 Progress in Pharmaceutical Sciences
关键词 S-腺苷甲硫氨酸 生化作用 药理 临床应用 S Adenosyl L methionine Biochemical effect Pharmacology Clinical application
分类号 R969 [医药卫生—药理学]
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参考文献26

  • 1Chavez M. SAMe:S-Adenosylmethionine[J]. Am J Health Sys Pharm, 2000,57: 119-125.
  • 2Mato J M, Albarez L, Ortiz P, et al. S-adenosyl-L-methionine synthetase and methionine metabolism deficiencies in cirrhosis[J].Adv Exp Med, 1994,368:113-119.
  • 3Osman E, Owen J S, Burroughs A K. Review article: Sadenosyl-L-methionine-a new therapeutic agent in liver disease[J]. Alinent Pharmacol Ther, 1993,7(1):21-23.
  • 4Chawla R K, Bonkovsky H L, Galambos J T. Biochemistry and pharmacology of S-adenosyl-L-methionine and rationale for its use in liver disease[J]. Drugs, 1990, 40 (suppl 3):98-110.
  • 5Almasio P, Bortolini M, Pagliaro L, et al. Role of S-adenosyl-L-methionine in the treatment of intrahepatic cholestasis [J]. Drugs, 1990,40(suppl 3): 111-119.
  • 6Bressa G M. S-adenosyl-L-methionine(SAMe) as antidepressant: meta-analysis of clinical studies[J]. Acta Neurol Scand Suppl, 1994,154:7-12.
  • 7Bottiglieri T, Hyland K, Reynolds E H. The clinical potential of ademetio-nine(S-adenosylmethionine) in neurological disorders[J]. Drugs, 1994,48: 137-146.
  • 8Bottiglieri T. Ademetionine (S-adenosylme-thionine) neurologicology: Implication for drug therapies in psychiatric and neurological disorders[J]. Expert Opin Invest Drugs, 1997,6(4):417-430.
  • 9刘平,顾牛范,翁史,舒良,李冰,周沫,沈渔村.S-腺苷蛋氨酸治疗抑郁症[J].中国心理卫生杂志,1998,12(2):94-96. 被引量：16
  • 10Berger R, Nowak H. A new medical approach to the treatment of osteoarthritis. Report of an open Phase Ⅳ study with ademetionine (Gumbaral)[J]. Am J Med, 1987,83(suppl 5A): 84-90.

二级参考文献1

  • 1Patrice Xavier Petit,Naoufal Zamzami,Jean-Luc Vayssière,Bernard Mignotte,Guido Kroemer,Maria Castedo. Implication of mitochondria in apoptosis[J] 1997,Molecular and Cellular Biochemistry(1-2):185～188

共引文献16

同被引文献290

引证文献30

二级引证文献137

药学进展
2001年 第3期

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