摘要
酵母表面展示是近年发展的一种新的蛋白表面展示技术 ,能够展示需糖基化作用、二硫键异构化等翻译后修饰才具功能活性的复杂真核蛋白。本文介绍了该技术的基本原理、研究进程、筛选方法。
Yeast surface display is a new technology developed in recent years,which displays protein of interest on the surface of yeast cell.It can be used to display complex eukaryotic proteins requiring post translational processing including glycosylation and efficient folding for functional activity. The basis of this technology, its development,methods of screening,its applications and perspective are mainly described in this paper. [
出处
《军事医学科学院院刊》
CSCD
北大核心
2001年第2期140-142,共3页
Bulletin of the Academy of Military Medical Sciences
基金
国家自然科学基金!资助项目 (3 980 0 13 3 )
