摘要
目的 观察海尔福口服液对砷中毒小白鼠血液生化指标的影响情况。方法以健康小白鼠为实验动物，随机分为正常对照组、中毒对照组和中毒治疗组，用亚砷酸钠为毒物、海尔福为治疗药物进行实验，６０ｄ后测定各组小白鼠的血红蛋白（Ｈｂ）、超氧化物歧化酶（ＳＯＤ）、谷胱甘肽（ＧＳＨ）和肌酐（Ｃｒ）等指标。结果中毒治疗组的血清ＳＯＤ活力、ＧＳＨ、血液Ｈｂ含量比中毒对照组明显升高，差异有显著性（Ｐ＜０．０５），而中毒对照组的血清Ｃｒ含量明显高于中毒治疗组和正常对照组（Ｐ＜０．０１）。结论海尔福口服液对砷中毒动物有治疗作用。
Objective Studying the effects of Haierfu on blood biochemical indices in mice with arsenic poisoning. Mothods Healthy mice were randomly divided into three groups: normal group、psisoned group and therapeutic group. Both the mice in poisoned group and therapeutic group were injected with Na2AsO3. Then the latter therapeutic group were treated with Haierfu. The serum glutachione(GSH).superoxide dismutase(SOD) and creatinine(Cr) and the blood hemoglobin(Hb) were measured after days.Result Comparing with the poisoned group, the vitality of SOD、the contents of GSH in serum and the contents of Hb in blood were obviously increased (P <0.05), while the Cr contents were gignficantly decreased(P < 0.01) in the therapeutic group. Conclusions The results in dicated that Haierfu can cure arsenic poisoning
出处
《中国地方病防治》
2001年第2期81-82,共2页
Chinese Journal of Control of Endemic Diseases
基金
广西区教育厅和卫生厅资助科研项目!项目编号:1992-1-32
