冬青和力抗栓对脑梗死患者血小板聚集率影响的对照研究

THE CONTRATEST STUDY ON THE VALUE OF PAgT ON THE PATIENTS OF CEREBRAL INFARCTION WITH DQ OR TP

目的 :比较冬青 (DQ)和力抗栓 (TP)对血小板聚集率 (PAgT)的影响。 方法 :对 10 0例血小板聚集率增高的住院脑梗死患者分别口服冬青 5 0mg 2次 /d和力抗栓 0 2 5g 1次 /d 4周进行对照研究。 结果 :治疗后两组 1min、5min血小板聚集率均显著降低 (P均 <0 0 5 ) ,但是两组间统计学上无差异 (P >0 0 5 )。结论 :冬青对血小板聚集率增高的脑梗死患者与力抗栓有同样显著作用。

Objective:To study the value of platelet aggregation rate(PAgT)on patients of cerebral infarction with Dong Qing(DQ) or ticlopidine(TP).Methods:100 patients diagnosed as cerebral infarction with higher PAgT were separated into two groups randomly. Therapeutical group(50/100) was treated with DQ `50mg Bid Po' and the control group (50/100) was treated with TP `0.25g Qd Po' with the therapeutical span for four months. The PAgT of these patients was detected before and after the treatment. The statistics were performed to compare the value of the two drugs.Results:After the treatment,the 1min-PAgT and 5min-PAgT of the two groups were decreased obviously(P<0.05),but no significant difference between the two groups(P>0.05)was found.Conclusion:The therapeutical effect of DQ on cerebral infarction with higher PAgT is definitely compared with TP.