氟康唑凝胶的研制及临床应用

Preparation and Clinical Application of Fluconazole Gel

目的:研制氟康唑凝胶,并制定质量标准。方法:采用一阶导数分光光度法进行含量测定。结果:氟康唑平均回收 率为(101.7±0.65)％,RSD为0.7％。结论:氟康唑凝胶制备工艺简单,含量测定简便,值得推广应用。

Objectives: To prepare a fluconazolr gel and establish a standard for quality control. Method: The content of fluconazole in gel was measured by first order derivative spectrophotometry. Results: The mean recovery rate of fluconazole was (101. 7 ± 0.65) % , RSD was 0.7%. Conclusion: The preparing technique of fluconazole gel is simple. The method of content determination is easy. It is worthy to popularzize and apply.