大鼠胃有腺区粘膜层微血管构筑的发育及衰老变化

The Study of Microvasculature of Glandular Mucosa of Rat Stomach during Developing and Aged

应用扫描电镜、透射电镜及血管铸型等技术方法 ,对初生、离乳、成年和老年 4个年龄段大鼠胃粘膜微血管构筑及毛细血管内皮细胞超微结构的发育及衰老变化进行了研究。结果表明 ,初生大鼠胃粘膜形成大量皱襞 ,微血管正处于分化、发育的过程中 ,尚未形成典型的构型 ;从离乳到老年 ,胃粘膜毛细血管形成明显的分区 ,胃粘膜层微血管构型为“树型” ;毛细血管内皮细胞的超微结构随发育、衰老呈明显的变化趋势 ,即毛细血管内皮细胞质膜突起的数量有增多的趋势 ,基底膜有增厚的趋势 ,而质膜小泡的数量没有明显的改变。

In our experiments, The morphological alterations and the development of microvasculature of the stomach wall and the endothelial cell at developing and aged have been observed by SEM,TEM and microvascular corrosion casting technique.The results showed: in the newborn rats, the capillary vessel of the gastric mucosal is folded or twisted, and not formed typical microvasculature. From the newborn rats to the aged rats, there are lots of subareas, which have the posterior venues as its center.The shape of the gastric mucosal microvascular is similar to a tree.During the aging, the ultrastructure of the endothelial cell changed, such as the number of plasmalemma tuber increase dramatically. The basal membrane has been thickened clearly.The number of the plasmalemmal vesicle is not changed.