用熔融结晶技术提纯人造麝香DDHI

Refinement of Musk DDHI by Melt Crystallization

用熔融结晶技术从DDHI混合物中分离提纯人造麝香DDHI,结晶的适宜条件为 :结晶时间2h ,降温速率 4℃ /h ,通氮气 ,发汗时升温速率为 6℃ /h ,发汗时间为 30min。经过二级结晶 ,w(DDHI) =99 2 % ,收率为 6 3 2 %。

Melt crystallization was used to purify mixture of musk DDHI. It was shown that the appropriate operation conditions were crystallizing time 2 h, cooling rate 4°C/h for crystallization, heating rate 6°C/h for sweating, and sweat time 30 min. After crystallization, purity of the product was higher than 99.2%, and the yield was 63.2%.