摘要
白色念珠菌的粘附与其表面甘露糖结构有关 ,为探讨阻断粘附的方法 ,我们采用体外法测定其对口腔上皮细胞的粘附数量 ,显示 :白色念珠菌粘附感染上皮细胞后 ,甘露糖可以在一定程度上减少粘附 ,绿慕安及刀豆素 A可以有效地减少粘附。
Mannose containing moieties on the surface of Cadida albicans could mediate the adherence of this yeasts to human epithelium. To study the methods of inhibiting adherence, we measured the quantity of adherecne of Cadida albicans to epithelial cells in vitro. The results showed that mannose can inhibited adherence partly, and PA MSHA (Pseudomonas aeruginosa with Mannose Sensitive hemagglutination Pili)vaccin and concanavalin A can inhibited adherence effectively after Cadida albicans adhered to epithelial cells. Therefore mannose and PA MSHA vaccin could prevent adhesion and infections.
出处
《中国微生态学杂志》
CAS
CSCD
2001年第3期164-165,共2页
Chinese Journal of Microecology
关键词
白色念珠菌
口腔上皮细胞
粘附
Cadida albicans
human epithelial cells
adherence