煤工尘肺复治肺结核两种治疗方案疗效分析

An analysis on the therapeutic effect of 3SHRZ/3HRZE/12HRE and 3SHRZ/9HRE on coal worker's pneumoconiosis-tuberculosis

目的 探讨煤工尘肺结核复治病例较佳的治疗方案。方法 对出院的煤工尘肺结核复治病例中应用 3SHRZ/ 3HRZE/ 12HRE 194例和 3SHRZ/ 9HRE 72例抗痨治疗疗效作回顾性分析。结果 痰菌阴转率 :治疗 6个月和疗程结束后 ,两种方案痰菌阴转率有显著性差异 (P <0 .0 5) ;胸片好转率也有显著性差别 (P <0 .0 5)。结论 煤工尘肺结核复治病例的治疗 ,采用 3SHRZ/ 3HRZE/ 12HRE方案 ,即强化阶段 6个月、疗程 18个月疗效较满意 ,不宜采用

Objective To probe into the better retreatment scheme for the coal worker's pneumoconiosis-tuberculosis treatment. Methods Analyse the therapeutic effect and the anti-tuberculosis treatment in the case in which 194 3SHRZ/3HRZE/12HRE and 73 3SHRZ/9HRE were applied on these patients who had been discharged from hospital. Results After 6 months treatment,both of these 2 treatment schemes were obviously different in the sputum tubercle bacillus negative convertion-rate on all kinds of the coal worker's pneumoconisis-tuberculosis(P<0.05); and so were they on the redution-rate of chest X-ray after the course of treatment (P<0.05). Conclusion The 6-month strengthened period-the scheme of the 3SHRZ/3HRZE/12HRE applied on the reteatment of the coal worker's pneumoconiosis-tuberculosis case,and the course of treatment was as long as 18 months. The therapeutic effect was quite satisfactory,so it is not appropriate to apply the 12-month scheme.