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FHIT基因与子宫颈癌

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摘要 定位于染色体 3p14.2的 FHIT基因是 1996年克隆的侯选抑癌基因。该基因包含脆性位点FRA3B和 t( 3;8)异位断裂位点。编码蛋白质具有 Ap3A水解酶。在子宫颈癌和其他肿瘤中 ,多有其缺失及基因异常。
出处 《国外医学(妇幼保健分册)》 2001年第2期64-66,共3页 Foreign Medical Sciences (Section of Maternal and Child Health)
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