肺癌伴恶性胸水的外科治疗

Surgery combined with other therapy for lung cancer with malignant pleural effusion

目的 探讨既消除胸水、治疗胸膜病变 ,又切除或控制原发病灶的方法。方法 对40例肺癌伴恶性胸水者行手术、免疫、介入或化疗。结果 所有病人胸水消失 ,2 9例死于术后 6～31个月 (平均 13个月 ) ,9例术后 5～ 5 2个月仍生存。结论 外科综合治疗肺癌伴恶性胸水效果显著。

Objective For the purposes of eliminating pleural effusions and treating pleural diseases meanwhile removing or controlling primary lung lesions.Methods Forty lung cancer patients with malignant pleural effusion were undergone serial therapy of operations,immunotherapy, intervention chemotherapy or chemotherapy.Results There were no operative deaths.The malignant pleural effusions were controlled after the therapy.Patients' general conditions were significantly improved.The mean survival time was 13 months(range,6 to 31 months).9 patients were still alive 5 to 52 months postoperatively.Conclusion The therapy sequence of operation(including VATS, chest drain),immunotherapy, intervention chemotherapy or chemotherapy has offered one of the best therapy choices for lung cancer with malignant pleural effusion at present. [