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一氧化氮吸入疗法治疗新生儿持续肺动脉高压的副作用研究 被引量:1

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摘要 目的 :探讨一氧化氮 (NO)吸入疗法治疗新生儿持续肺动脉高压的疗效及副作用。方法 :对 2 4例新生儿持续肺动脉高压患儿给予NO吸入疗法治疗 ,观察全身氧合情况的变化 ,同时持续监测心率、血压 ,吸入前后检测血高铁血红蛋白定量并监测凝血功能的改变。结果 :2 4例患儿中 19例 (79 2 % )治疗后氧合情况显著改善 ,监测心率、血压无明显改变 ,高铁血红蛋白定量增高均在可以接受的范围内 ,凝血功能无明显改变。结论 :NO吸入疗法治疗新生儿持续肺动脉高压有显著疗效 。
出处 《中国优生与遗传杂志》 2001年第3期91-92,共2页 Chinese Journal of Birth Health & Heredity
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同被引文献6

  • 1邵肖梅,叶鸿瑁,丘小汕.实用新生儿学[M].4版.北京:人民卫生出版社,2011:871-872.
  • 2余章斌,韩树萍,郭锡熔.吸入一氧化氮治疗早产儿低氧性呼吸衰竭的Meta分析[J].中国循证儿科杂志,2007,2(5):327-337. 被引量:9
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  • 4George TN,Johnson KJ,Bates JN, et al. The effect of inhaled nitric oxide therapy on bleeding time and platelet aggregation in neonates[J]. J Pediatr, 1998,132(4): 731-734.
  • 5Subhedar NV, Shaw NJ. Neurodevelopmental outcome with inhaled nitric oxide therapy[J]. J Pediatr, 1999,135 (2) :266-267.
  • 6Hascoet J. M, Fresson J, Claris O, et al. The safety and efficacy of nitric oxide therapy in premature infants[J]. J Pediatr, 2005,146(3) :318-323.

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